Category: Vasopressin Receptors
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Gray, amino acid positions that were mutated during the random maturation process
Gray, amino acid positions that were mutated during the random maturation process. == In Silico-assisted Affinity Maturation of hu3F8 by Site-directed Mutagenesis == Because parental hu3F8 is not immunogenic in individuals,4we wanted to limit the number of mutations to avoid neoantigens and epitope spread (6). interactions with the sialic acid groups of GD2. Two mutations,…