Category: Sphingosine N-acyltransferase
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Important exclusion criteria included the following: prior exposure to adalimumab or another TNF inhibitor if the TNF inhibitor was discontinued for lack of efficacy or safety reasons or the drug had not been washed out for 5 halflives; prior exposure to other nonTNF inhibitors or IL17 inhibitor biologic DMARDs, unless washed out for 5 halflives; current treatment with standard synthetic DMARDs other than methotrexate, sulfasalazine, and hydroxychloroquine; having received orally administered prednisone or its comparative at 10 mg/day within 30 days of the baseline visit; current pregnancy or breastfeeding; and presence of active tuberculosis, chronic recurring infections, or active viral infections if the investigator assessed that the patient would be an unsuitable candidate for the study
Important exclusion criteria included the following: prior exposure to adalimumab or another TNF inhibitor if the TNF inhibitor was discontinued for lack of efficacy or safety reasons or the drug had not been washed out for 5 halflives; prior exposure to other nonTNF inhibitors or IL17 inhibitor biologic DMARDs, unless washed out for 5 halflives;…